Human Activin A protein (Animal-Free)
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| 产品名称 | Human Activin A protein (Animal-Free) |
|---|---|
| 中文名称 | 重组人/小鼠/大鼠Activin A（无动物源） |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | >98 % as determined by SDS-PAGE |
| 内毒素 | < 0.1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured by its ability to inhibit proliferation of MPC-11 cells. The ED50 for this effect is 0.013 ng/mL. |
| 基因编号 | 3624 |
| 蛋白链接 | http://www.uniprot.org/uniprot/P08476 |
| 别名 | rHuActivin A; Inhibin beta A chain; INHBA; Activin A ACV-A |
| 蛋白序列 | GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS |
| 蛋白标签 | C-His |
| 预测分子量 | The Human/Mouse/RatActivin A consists of 116 amino acids and predicts a molecular mass of 13.0 kDa |
| 产品形式 | Lyophilized from sterile 20mM Tris, 50mM NaCl, pH 8.0. |
| 使用方式 | Lyophilized Human/Mouse/Rat Activin A protein product should be stored desiccated below-20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Activin A, a member of TGF-β superfamily, is a disulfide-linked dimer protein, which was originally purified from gonadal fluid as protein to stimulate the release of pituitary follicle-stimulating hormone (FSH). Inhibins are involved in regulating many different functions, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythrocyte differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Many studies have shown that it can play a significant role in inducing islet β cell differentiation under the combined action of other factors. The recombinant Human Activin A has sequence identity with Mouse and RatActivin A protein. |
*本产品仅供科研试验用，不可直接用于人体。
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