| 产品名称 | Human FGF-17 protein |
|---|---|
| 中文名称 | 重组人成纤维细胞生长因子17 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | >95 % as determined by SDS-PAGE |
| 内毒素 | < 0.1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured in a cell proliferation assay using NIH-3T3 mouse fibroblast cells. The EC50 for this effect is 23.58 ng/mL. |
| 基因编号 | 8822 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/O60258/entry#sequences |
| 别名 | fibroblast growth factor 17, FGFH, FGF17 |
| 蛋白序列 | TQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT |
| 蛋白标签 | Tag Free |
| 预测分子量 | The recombinant Human FGF-17 consists of 194 amino acids and predicts a molecular mass of 22.6 kDa. |
| 产品形式 | Lyophilized from 20 mM Tris-HCl, 50mM NaCl, pH8.0. |
| 使用方式 | Lyophilized protein product should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days . For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Fibroblast Growth Factor 17(FGF-17) is a member of the heparin - binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF-17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition, FGF-17 stimulates the proliferation and activation of cells that express FGF receptors. |
*本产品仅供科研试验用，不可直接用于人体。
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