| 产品名称 | Human FGF1/FGF acidic Protein |
|---|---|
| 中文名称 | 重组人酸性成纤维细胞生长因子 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | >98% as determined by SDS-PAGE |
| 内毒素 | < 1.0 EU per µg of the protein as determined by the LAL method. |
| 生物活性 | Measured by its ability to induce proliferation in Balb/3T3 cells. The ED50 for this effect is 23.73 ng/mL. The specific activity of recombinant Human FGF1/FGF acidic protein is approximately >4.21 x 104 IU/mg. |
| 基因编号 | 2246 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P05230/entry |
| 别名 | FGF-1; Acidic fibroblast growth factor (aFGF); Endothelial cell growth factor (ECGF); Heparin-binding growth factor 1 (HBGF-1) |
| 蛋白序列 | MAEGEITTFTALTEKFNLPPGNYKKPKLLYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILFLPLPVSSD |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human FGF1 consists of 140 amino acids and has a predicted molecular mass of 15.5 kDa. |
| 产品形式 | Lyophilized from sterile 20mM tris 50mM NaCl, pH 6.5. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human FGF1 protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature |
| 储存条件 | Store at -20℃ |
| 产品背景 | FGF1, also known as FGF acidic, ECGF,aFGF and HBGF-1, is a nonglycosylated member of the FGF family of mitogenic peptides. FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. FGF1 protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer. |
*本产品仅供科研试验用，不可直接用于人体。
暂无文献引用信息