| 产品名称 | Mouse bFGF Protein |
|---|---|
| 中文名称 | 重组小鼠碱性成纤维细胞生长因子 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | > 98 % as determined by SDS-PAGE |
| 内毒素 | < 0.1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.11 ng/mL. The specific activity of recombinant Mouse bFGF is approximately >9.09 x 106 IU/mg. |
| 基因编号 | 14173 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P15655/entry |
| 别名 | BFGF; FGF-2; FGFB; HBGF-2; Fibroblast growth factor 2; FGF2 |
| 蛋白序列 | MAASGITSLPALPEDGGAAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHVKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTEECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Mouse bFGF protein consists of 146 amino acids and predicts a molecular mass of 18.5 kDa. |
| 产品形式 | Lyophilized from sterile 150 mM NaCl 20mM PB , pH 7.4. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse bFGF protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies. |
*本产品仅供科研试验用，不可直接用于人体。
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