| 产品名称 | Human FGF9 Protein |
|---|---|
| 中文名称 | 重组人成纤维细胞生长因子9 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | > 96% as determined by SDS-PAGE |
| 内毒素 | < 1EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured by its ability to induce proliferation in Balb/3T3 cells. The ED50 for this effect is 1.180 ng/mL. The specific activity of recombinant Human FGF 9 Protein is approximately >2.857 x 106 IU/mg. |
| 基因编号 | 2254 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P31371/entry |
| 别名 | FGF-9; Glia-activating factor (GAF); Heparin-binding growth factor 9 (HBGF-9) |
| 蛋白序列 | MAPLGEVGNYFGVQDAVPFGNVPVLPVDSPVLLSDHLGQSEAGGLPRGPAVTDLDHLKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTRTKRHQKFTHFLPRPVDPDKVPELYKDILSQS |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human FGF 9 consists of 206 amino acids and predicts a molecular mass of 23.2 kDa. |
| 产品形式 | Lyophilized from 20mM Tris 150mM NaCl PH:8.0. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human FGF 9 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Fibroblast growth factor 9 (FGF9) also known as Glia-activating factor or Heparin-binding growth factor 9, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis. FGF9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. FGF9 may have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors. |
*本产品仅供科研试验用，不可直接用于人体。
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