| 产品名称 | Human VEGF121 Protein |
|---|---|
| 中文名称 | 重组人血管内皮生长因子121 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | > 98 % as determined by SDS-PAGE |
| 内毒素 | <1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | The immobilized human vascular endothelial growth factor 121 at a dose of 1 μg/ml (100 μl/well) can bind to human vascular endothelial growth factor receptor 2, with an EC50 of human vascular endothelial growth factor receptor 2 of 156.5 ng/mL. The specific activity of recombinant Human VEGF121 protein is approximately 6.39 x 103 IU/mg. |
| 基因编号 | 7422 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P15692/entry |
| 别名 | Vascular permeability factor (VPF); VEGF121; |
| 蛋白序列 | MAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQENCDKPRR |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human VEGF121 consists of 121 amino acids and predicts a molecular mass of 14 kDa. |
| 产品形式 | Lyophilized from sterile PBS, pH 7.4. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human VEGF121 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. VEGF signals through three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Due to its increased acidity, Human VEGF121 circulates more freely than other VEGF forms, which bind more tightly with vascular heparin sulfates. |
*本产品仅供科研试验用，不可直接用于人体。
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