| 产品名称 | Human IFN-α2a Protein |
|---|---|
| 中文名称 | 重组人干扰素α2a |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | > 99 % as determined by SDS-PAGE |
| 内毒素 | <1.0 EUper μg of the protein as determined by the LAL method |
| 生物活性 | Measured by a cytotoxicity assay using TF-1 Cells. The ED50 for this effect is 0.3301 ng/mL |
| 基因编号 | 3440 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P01563/entry |
| 别名 | Interferon alpha-2; IFN-alpha-2; Interferon alpha-A |
| 蛋白序列 | MALTFALLVALLVLSCKSSCSVGCDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human IFN-α2a consists of 165 amino acids and predicts a molecular mass of 19.4 kDa |
| 产品形式 | Lyophilized from 20mM Tris, 150mM NaCl, pH 8.0. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions |
| 运输方式 | The product is shipped at ambient temperature |
| 储存条件 | Store at -20°C |
| 产品背景 | :At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end. IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects |
*本产品仅供科研试验用，不可直接用于人体。
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