Human GM-CSF, His tag(Animal-Free)
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| 产品名称 | Human GM-CSF, His tag(Animal-Free) |
|---|---|
| 中文名称 | 重组人粒细胞-巨噬细胞集落刺激因子（无动物源）His-标签 |
| 种属 | Human |
| 表达宿主 | HEK 293 Cells |
| 纯度 | >98% as determined by SDS-PAGE |
| 内毒素 | < 1.0 EU per µg of the protein as determined by the LAL method |
| 生物活性 | Measured in a cell proliferation assay using TF-1 cells. The ED50 for this effect is 0.3187 ng/mL.The specific activity of recombinant Human GM-CSF is approximately >3.12 x 106 IU/mg. |
| 基因编号 | 1437 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P04141/entry |
| 别名 | Colony-stimulating factor (CSF) Molgramostin Sargramostim |
| 蛋白序列 | MWLQSLLLLGTVACSISAPARSPSPSTQPWEHVNAIQEARRLLNLSRDTAAEMNETVEVISEMFDLQEPTCLQTRLELYKQGLRGSLTKLKGPLTMMASHYKQHCPPTPETSCATQIITFESFKENLKDFLLVIPFDCWEPVQE |
| 蛋白标签 | C-His |
| 预测分子量 | The recombinant human GM-CSF consists of 127 amino acids and predicts a molecular mass of 14.5 kDa. It migrates as an approximately 23.8 kDa band in SDS-PAGE under reducing conditions due to glycosylation. |
| 产品形式 | Lyophilized from sterile PBS, pH 7.4 |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human GM-CSF protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20°C |
| 产品背景 | Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. GM-CSF is used therapeutically in myeloid reconstitution following bone marrow transplant, bone marrow transplant engraftment failure or delay, mobilization and following transplantation of autologous peripheral blood progenitor cells, and following induction chemotherapy in older adults with acute myelogenous leukemia (AML) |
*本产品仅供科研试验用，不可直接用于人体。
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