| 产品名称 | Mouse GM-CSF Protein |
|---|---|
| 中文名称 | 重组小鼠粒细胞巨噬细胞集落刺激因子 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | > 96 % as determined by SDS-PAGE |
| 内毒素 | < 1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured in a cell proliferation assay using FDC-P1 cells. The ED50 for this effect is 1.203 ng/mL. The Specific activity of recombinant Mouse GM-CSF is approximately > 8.31x106 IU/mg. |
| 基因编号 | 12981 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P01587/entry |
| 别名 | Colony-stimulating factor (CSF) |
| 蛋白序列 | MWLQNLLFLGIVVYSLSAPTRSPITVTRPWKHVEAIKEALNLLDDMPVTLNEEVEVVSNEFSFKKLTCVQTRLKIFEQGLRGNFTKLKGALNMTASYYQTYCPPTPETDCETQVTTYADFIDSLKTFLTDIPFECKKPGQK |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Mouse GM-CSF consists of 124 amino acids and predicts a molecular mass of 14.2 kDa |
| 产品形式 | Liquid in from sterile 20 mM Tris, 150 mM NaCl ,5% Glycerol, pH 8.0. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to diluted the protein using the PBS buffer or Protein storage solution to working concentration. |
| 运输方式 | The product is shipped at gel pack with blue ice. |
| 储存条件 | Store at -20°C |
| 产品背景 | Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factorthat can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by anumber of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cellsand fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophageprogenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. GM-CSF has a functional role on nonhematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally, GM-CSF canalso stimulate the proliferation of a number of tumor cell lines, including osteogenic sarcoma, carcinoma andadenocarcinoma cell lines. |
*本产品仅供科研试验用，不可直接用于人体。
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