| 产品名称 | Human G-CSF Protein |
|---|---|
| 中文名称 | 重组人粒细胞集落刺激因子 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | >98% as determined by SDS-PAGE |
| 内毒素 | < 1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured by its ability to induce proliferation in M-NFS-60 cells. The ED50 for this effect is 0.2569 ng/mL, The specific activity of recombinant Human G-CSF Protein is approximately3.9 x 106 IU/mg. |
| 基因编号 | 1441 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/Q99062/entry |
| 别名 | Human G-CSF |
| 蛋白序列 | MARLGNCSLTWAALIILLLPGSLEECGHISVSAPIVHLGDPITASCIIKQNCSHLDPEPQILWRLGAELQPGGRQQRLSDGTQESIITLPHLNHTQAFLSCCLNWGNSLQILDQVELRAGYPPAIPHNLSCLMNLTTSSLICQWEPGPETHLPTSFTLKSFKSRGNCQTQGDSILDCVPKDGQSHCCIPRKHLLLYQNMGIWVQAENALGTSMSPQLCLDPMDVVKLEPPMLRTMDPSPEAAPPQAGCLQLCWEPWQPGLHINQKCELRHKPQRGEASWALVGPLPLEALQYELCGLLPATAYTLQIRCIRWPLPGHWSDWSPSLELRTTERAPTVRLDTWWRQRQLDPRTVQLFWKPVPLEEDSGRIQGYVVSWRPSGQAGAILPLCNTTELSCTFHLPSEAQEVALVAYNSAGTSRPTPVVFSESRGPALTRLHAMARDPHSLWVGWEPPNPWPQGYVIEWGLGPPSASNSNKTWRMEQNGRATGFLLKENIRPFQLYEIIVTPLYQDTMGPSQHVYAYSQEMAPSHAPELHLKHIGKTWAQLEWVPEPPELGKSPLTHYTIFWTNAQNQSFSAILNASSRGFVLHGLEPASLYHIHLMAASQAGATNSTVLTLMTLTPEGSELHIILGLFGLLLLLTCLCGTAWLCCSPNRKNPLWPSVPDPAHSSLGSWVPTIMEEDAFQLPGLGTPPITKLTVLEEDEKKPVPWESHNSSETCGLPTLVQTYVLQGDPRAVSTQPQSQSGTSDQVLYGQLLGSPTSPGPGHYLRCDSTQPLLAGLTPSPKSYENLWFQASPLGTLVTPAPSQEDDCVFGPLLNFPLLQGIRVHGMEALGSF |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human G-CSF protein consists of 174 amino acids with a Met in N terminal and predicts a molecular mass of 18.7 kDa. |
| 产品形式 | Liquid in from PBS. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to diluted the protein using the PBS buffer or Protein storage solution to working concentration |
| 运输方式 | The product is shipped at gel pack with blue ice. |
| 储存条件 | Store at -20°C |
| 产品背景 | Granulocyte colony-stimulating factor (G-CSF) is a member of the CSF family of glycoproteins that regulate hematopoietic cell proliferation, differentiation, and function. It is a key cytokine involved in the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf & Nicola). G-CSF causes a range of effects including a transient reduction of SDF-1 expression, the activation of metalloproteases that cleave VCAM-1 , and the release of norepinephrine from the sympathetic nervous system, leading to the release or mobilization of hematopoietic stem cells from the bone marrow into the periphery. |
*本产品仅供科研试验用，不可直接用于人体。
暂无文献引用信息