| 产品名称 | Mouse G-CSF Protein,His tag |
|---|---|
| 中文名称 | 重组小鼠粒细胞集落刺激因子，His-标签 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | > 98 % as determined by SDS-PAGE |
| 内毒素 | < 0.1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured by its ability to induce proliferation in M-NFS-60 cells. The ED50 for this effect is 1.916 ng/mL. The Specific activity of recombinant Mouse G-CSF is approximately > 5.21x106 IU/mg. |
| 基因编号 | 12985 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P09920/entry |
| 别名 | Mouse G-CSF |
| 蛋白序列 | MAQLSAQRRMKLMALQLLLWQSALWSGREAVPLVTVSALPPSLPLPRSFLLKSLEQVRKIQASGSVLLEQLCATYKLCHPEELVLLGHSLGIPKASLSGCSSQALQQTQCLSQLHSGLCLYQGLLQALSGISPALAPTLDLLQLDVANFATTIWQQMENLGVAPTVQPTQSAMPAFTSAFQRRAGGVLAISYLQGFLETARLALHHLA |
| 蛋白标签 | C-His |
| 预测分子量 | The recombinant Mouse G-CSF consists of 178 amino acids and predicts a molecular mass of 19.8 kDa. |
| 产品形式 | Lyophilized from sterile 20mM Tris, 150mM NaCl, 5% Sucrose, 5% Mannitol, pH9.0 |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Mouse G-CSF protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature |
| 储存条件 | Store at -20°C |
| 产品背景 | Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent. |
*本产品仅供科研试验用，不可直接用于人体。
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