| 产品名称 | Mouse M-CSF Protein, His tag |
|---|---|
| 中文名称 | 重组小鼠巨噬细胞集落刺激因子，His-标签 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | > 95 % as determined by SDS-PAGE |
| 内毒素 | <1EUper μgof the protein by the LALmethod. |
| 生物活性 | Measured by its ability to induce proliferation in M-NFS-60 cells. The ED50 for this effect is 0.1179 ng/mL. The specific activity of recombinant Mouse M-CSF, His-tag Protein, His-tag is approximately >8.48 x 106 IU/mg. |
| 基因编号 | 12977 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P07141/entry |
| 别名 | Proteoglycan macrophage colony-stimulating factor |
| 蛋白序列 | MTARGAAGRCPSSTWLGSRLLLVCLLMSRSIAKEVSEHCSHMIGNGHLKVLQQLIDSQMETSCQIAFEFVDQEQLDDPVCYLKKAFFLVQDIIDETMRFKDNTPNANATERLQELSNNLNSCFTKDYEEQNKACVRTFHETPLQLLEKIKNFFNETKNLLEKDWNIFTKNCNNSFAKCSSRDVVTKPDCNCLYPKATPSSDPASASPHQPPAPSMAPLAGLAWDDSQRTEGSSLLPSELPLRIEDPGSAKQRPPRSTCQTLESTEQPNHGDRLTEDSQPHPSAGGPVPGVEDILESSLGTNWVLEEASGEASEGFLTQEAKFSPSTPVGGSIQAETDRPRALSASPFPKSTEDQKPVDITDRPLTEVNPMRPIGQTQNNTPEKTDGTSTLREDHQEPGSPHIATPNPQRVSNSATPVAQLLLPKSHSWGIVLPLGELEGKRSTRDRRSPAELEGGSASEGAARPVARFNSIPLTDTGHVEQHEGSSDPQIPESVFHLLVPGIILVLLTVGGLLFYKWKWRSHRDPQTLDSSVGRPEDSSLTQDEDRQVELPV |
| 蛋白标签 | C-His |
| 预测分子量 | The recombinant Mouse M-CSF consists of 230 amino acids and predicts a molecular mass of 26.1 kDa |
| 产品形式 | Lyophilized from 20 mM Tris-HCl, 150mM NaCl, pH8.5 |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20°C |
| 产品背景 | M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis |
*本产品仅供科研试验用，不可直接用于人体。
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