| 产品名称 | Rat SCF Protein,His tag |
|---|---|
| 中文名称 | 重组大鼠干细胞因子，His-标签 |
| 种属 | Rat |
| 表达宿主 | E. coli |
| 纯度 | > 99 % as determined by SDS-PAGE |
| 内毒素 | <1.0 EUper μg of the protein as determined by the LAL method. |
| 生物活性 | Measured in a cell proliferation assay using TF-1. The ED50 for this effect is typically 0.1737 ng/mL. The specific activity of recombinant Rat SCF is approximately >5.76 x 106 IU/mg. |
| 基因编号 | 60427 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P21581/entry |
| 别名 | Hematopoietic growth factor KL Mast cell growth factor (MGF) Stem cell factor (SCF) c-Kit ligand |
| 蛋白序列 | MKKTQTWIITCIYLQLLLFNPLVKTQEICRNPVTDNVKDITKLVANLPNDYMITLNYVAGMDVLPSHCWLRDMVTHLSVSLTTLLDKFSNISEGLSNYSIIDKLGKIVDDLVACMEENAPKNVKESLKKPETRNFTPEEFFSIFNRSIDAFKDFMVASDTSDCVLSSTLGPEKDSRVSVTKPFMLPPVAASSLRNDSSSSNRKAAKSPEDPGLQWTAMALPALISLVIGFAFGALYWKKKQSSLTRAVENIQINEEDNEISMLQQKEREFQEV |
| 蛋白标签 | N-His |
| 预测分子量 | The Recombinant Rat SCF Protein consists of 170 amino acids and predicts a molecular mass of 18.47KDa |
| 产品形式 | Lyophilized from sterile 20 mM Tris with 150 mM NaCl, pH 7.4 |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Recombinant Rat SCF Protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature |
| 储存条件 | Store at -20°C |
| 产品背景 | Stem cell factor (SCF), as a key ligand of KIT, regulates cell survival, proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration, and melanogenesis. Binding to KIT activates signaling pathways involving phosphorylation events, key kinases (AKT1, RAS, RAF1, MAPK1/ERK2, MAPK3/ERK1), STAT family members, and PLCG1. SCF Protein, Rat (His) is the recombinant rat-derived SCF protein, expressed by E. coli with C-6*His labeled tag. |
*本产品仅供科研试验用，不可直接用于人体。
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