| 产品名称 | Human IL-3 Protein |
|---|---|
| 中文名称 | 重组人白介素3 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | > 98 % as determined by SDS-PAGE |
| 内毒素 | < 0.1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is 0.2575 ng/mL,The specific activity of recombinant Human IL-3 protein is approximately 3.88 x 106 IU/mg. |
| 基因编号 | 3562 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P08700/entry |
| 别名 | Hematopoietic growth factor; Mast cell growth factor (MCGF); Multipotential colony-stimulating factor; P-cell-stimulating factor; |
| 蛋白序列 | MSRLPVLLLLQLLVRPGLQAPMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human IL-3 consists of 133 amino acids and has a predicted molecular mass of 15.2 kDa. |
| 产品形式 | Lyophilized from sterile PBS, pH 7.4. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-3 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | IL-3 (Interleukin 3), also known as IL3, is a potent growth-promoting cytokine that belongs to the IL-3 family. IL-3 also belongs to the group of interleukins. Interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation, and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. |
*本产品仅供科研试验用，不可直接用于人体。
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