| 产品名称 | Human/Mouse BMP-2 Protein |
|---|---|
| 中文名称 | 重组人/小鼠骨形态发生蛋白2 |
| 种属 | Human/ Mouse |
| 表达宿主 | E. coli |
| 纯度 | >95 % as determined by SDS-PAGE |
| 内毒素 | <0.1 EU per μg of the protein by the LAL method. |
| 生物活性 | Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED₅₀ for this effect is <10 ng/mL. As shown in the figure below, the number of positive cells increased as the concentration of BMP-2 protein was added, and this effect was measured by the TRAP kit. |
| 基因编号 | 650 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P12643/entry |
| 别名 | Bone morphogenetic protein 2A (BMP-2A) |
| 蛋白序列 | QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human/Mouse BMP-2 consists of 114 amino acids and predicts a molecular mass of 13 kDa. |
| 产品形式 | Lyophilized from sterile 20mM Tris, 50 mM NaCl, pH 8.0 |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature |
| 储存条件 | Store at -20°C |
| 产品背景 | Bone morphogenetic protein-2 (BMP-2) is a kind of bone growth regulator, belonging to protein transforming growth factor-β(TGF-β) superfamily. BMP-2 protein is involved in hedgehog pathway, TGF-β signaling pathway and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMP, which have been proved to be effective in inducing osteoblast differentiation in many cell types. The active form of BMP-2 can be composed of dimers of two identical proteins or heterodimers of two related bone morphogenetic proteins |
*本产品仅供科研试验用，不可直接用于人体。
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