| 产品名称 | Mouse LIF Protein, C-His tag |
|---|---|
| 中文名称 | 重组小鼠白血病抑制因子，C-His标签 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | >98% as determined by SDS-PAGE |
| 内毒素 | < 0.01 EU per µg of the protein as determined by the LAL method |
| 生物活性 | Measured by its ability to induce proliferation in M-NFS-60 cells. The ED50 for this effect is 8.023 ng/mL. The Specific activity of recombinant Mouse LIF protein is approximately > 1.24x106 IU/mg. |
| 基因编号 | 16878 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P09056/entry |
| 别名 | Differentiation-stimulating factor (D factor) |
| 蛋白序列 | MKVLAAGIVPLLLLVLHWKHGAGSPLPITPVNATCAIRHPCHGNLMNQIKNQLAQLNGSANALFISYYTAQGEPFPNNVEKLCAPNMTDFPSFHGNGTEKTKLVELYRMVAYLSASLTNITRDQKVLNPTAVSLQVKLNATIDVMRGLLSNVLCRLCNKYRVGHVDVPPVPDHSDKEAFQRKKLGCQLLGTYKQVISVVVQAF |
| 蛋白标签 | C-His |
| 预测分子量 | The recombinant Mouse LIF protein consists of 186 amino acids and has a predicted molecular mass of 20.5 kD. |
| 产品形式 | Lyophilized from sterile PBS, pH 7.4 |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse LIF protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20°C |
| 产品背景 | Leukemia inhibitory factor (LIF) is a 20 kD protein that belongs to the IL-6 receptor family, is a pleiotropic factor produced by multiple cell types, including T cells, myelomonocytic lineages, fibroblasts, liver, heart and melanoma. LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes |
*本产品仅供科研试验用，不可直接用于人体。
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