| 产品名称 | Mouse IL-6 Protein |
|---|---|
| 中文名称 | 重组小鼠白介素6 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | > 99% as determined by SDS-PAGE |
| 内毒素 | < 0.1 EU per μg of the protein as determined by the LAL method. |
| 生物活性 | Measured in a cell proliferation assay using M-NFS60. The ED50 for this effect is typically 1.75 ng/mL. The specific activity of recombinant Mouse IL6 is approximately >5.71 x 105 IU/mg. |
| 基因编号 | 16193 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P08505/entry |
| 别名 | B-cell hybridoma growth factor; Interleukin HP-1 |
| 蛋白序列 | MKFLSARDFHPVAFLGLMLVTTTAFPTSQVRRGDFTEDTTPNRPVYTTSQVGGLITHVLWEIVEMRKELCNGNSDCMNNDDALAENNLKLPEIQRNDGCYQTGYNQEICLLKISSGLLEYHSYLEYMKNNLKDNKKDKARVLQRDTETLIHIFNQEVKDLHKIVLPTPISNALLTDKLESQKEWLRTKTIQFILKSLEEFLKVTLRSTRQT |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Mouse IL-6 consists of 187 amino acids and predicts a molecular mass of 21.9 kDa. |
| 产品形式 | Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 7.4. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20°C |
| 产品背景 | Interleukin-6 (IL-6) is a pro-inflammatory cytokine that also has an important role in immunity. Mouse IL-6 appears to be directly involved in the responses that occur after infection and injury and may prove to be as important as IL-1 in regulating the acute phase response. Mouse IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells, including fibroblasts, myeloid progenitor cells, T cells, B cells and hepatocytes. IL-6 has a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, nerve cells differentiation in hepatocytes, and acute phase reactants. |
*本产品仅供科研试验用，不可直接用于人体。
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