| 产品名称 | Mouse IL-2 Protein |
|---|---|
| 中文名称 | 重组小鼠白介素2 |
| 种属 | Mouse |
| 表达宿主 | E. coli |
| 纯度 | > 95 % as determined by SDS-PAGE |
| 内毒素 | < 1 EU per μgof the protein as determined by the LALmethod. |
| 生物活性 | Measured by its ability to induce proliferation in CTLL-2 cells. The ED50 for this effect is 0.05203 ng/mL. The Specific activity of recombinant Mouse IL-2 is approximately > 1.92x107 IU/mg. |
| 基因编号 | 16183 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P04351/entry |
| 别名 | T-cell growth factor (TCGF) |
| 蛋白序列 | MYSMQLASCVTLTLVLLVNSAPTSSSTSSSTAEAQQQQQQQQQQQQHLEQLLMDLQELLSRMENYRNLKLPRMLTFKFYLPKQATELKDLQCLEDELGPLRHVLDLTQSKSFQLEDAENFISNIRVTVVKLKGSDNTFECQFDDESATVVDFLRRWIAFCQSIISTSPQ |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Mouse IL-2 (NP_032392.1) (Ala21-Gln169) consists of 149 amino acids and has a predicted molecular mass of 17 kDa. |
| 产品形式 | Lyophilized from sterile 20mM Tris, 300mM NaCl, pH 8.0. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Mouse IL-2 protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Interleukin-2 (IL-2), also known as T cell growth factor, is a member of the cytokine family, including IL-4, IL-7, IL-9, IL-15, and IL-21. Each member of this family has a bundle of four α spirals. IL-2 signals through IL-2 receptors, which are complexes of dendritic subunits called α,β, and γ. γIL-2R is common to the cytokine receptors of all members of the cytokine family. Mature IL2 mice share 56% and 73% of aa sequence identity with human and rat IL-2, respectively. Produced by CD4+ T cells, CD8+ T cells, γ δ T cells, B cells, dendritic cells, and eosinophils, IL-2 plays a vital role in key immune system function, tolerance, and immunity, primarily due to its potent stimulating activity against T cells. Therefore, IL-2 may be a key cytokine that naturally suppresses autoimmunity. |
*本产品仅供科研试验用，不可直接用于人体。
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