Human FGF-8a Protein, His tag (Animal-Free)
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| 产品名称 | Human FGF-8a Protein, His tag (Animal-Free) |
|---|---|
| 中文名称 | 重组人生长因子8a，His-标签（无动物源） |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | > 95 % as determined by SDS-PAGE |
| 内毒素 | <1 EU per μg of the protein by the LAL method. |
| 生物活性 | Measure by its ability to induce 3T3 cells proliferation.The ED50 for this effect is <2 ng/mL. The specific activity of recombinant Human FGF8a is approximately >5 x105 IU/ mg. |
| 基因编号 | 30538 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/O57341/entry |
| 别名 | Fibroblast growth factor 8a; AIGF; HBGF-8; FGF8 |
| 蛋白序列 | MSPPNFTQHVSEQSKVTDRVSRRLIRTYQLYSRTSGKHVQVLANKKINAMAEDGDVHAKLIVETDTFGSRVRIKGAETGFYICMNRRGKLIGKKNGLGKDCIFTEIVLENNYTALQNVKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPKGHQIAEHRPFDFINYPFNRRTKRTRYSGER |
| 蛋白标签 | C-His |
| 预测分子量 | The recombinant Human FGF-8a consists of 182 amino acids and predicts a molecular mass of 22.14 kDa. |
| 产品形式 | Liquid in from sterile 20 mM Tris, 150 mM NaCl, pH 8.0, 5% Glycerol,1 mM EDTA. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to diluted the protein using the PBS buffer or Protein storage solution to working concentration. |
| 运输方式 | The product is shipped at gel pack with blue ice. |
| 储存条件 | Store at -20°C |
| 产品背景 | FGF-8 is a heparin binding growth factor belonging to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. There are 4 known alternate spliced forms of FGF8; FGF-8A, FGF-8B, FGF-8E and FGF-8F. The human and murine FGF-8A and B are identical, unlike human and mouse FGF-8E and F, which are 98% identical. FGF-8 targets mammary carcinoma cells and other cells expressing the FGF receptors. |
*本产品仅供科研试验用，不可直接用于人体。
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