| 产品名称 | Human IL-4 Protein |
|---|---|
| 中文名称 | 重组人白介素4 |
| 种属 | Human |
| 表达宿主 | E. coli |
| 纯度 | > 96 % as determined by SDS-PAGE |
| 内毒素 | < 1 EU per μg of the protein by the LAL method. |
| 生物活性 | Measured in a cell proliferation assay using TF -1. The ED50 for this effect is typically 0.144 ng/mL. The specific activity of recombinant Human IL4 is approximately >6.94 x 106 IU/mg. |
| 基因编号 | 3565 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P05112/entry |
| 别名 | IL-4; B-cell stimulatory factor 1 (BSF-1); BinetrakinLymphocyte stimulatory factor 1; Pitrakinra |
| 蛋白序列 | MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTELTVTDIFAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS |
| 蛋白标签 | Tag free |
| 预测分子量 | The recombinant Human IL-4 consists of 129 amino acids and predicts a molecular mass of 15.1 kDa. |
| 产品形式 | Lyophilized from sterile 20 mM Tris-HCl, 150 mM NaCl, pH7.4. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13. IL-4, originally designated as B-cell growth factor-1 (BSFl), is described in the supernatant of activated EL-4 thymoma cells as a factor that can co-stimulate B-cells activated with submitogenic concentrations of anti-IgM. |
*本产品仅供科研试验用，不可直接用于人体。
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