Human IL-3 Protein, His tag (Animal-Free)
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| 产品名称 | Human IL-3 Protein, His tag (Animal-Free) |
|---|---|
| 中文名称 | 重组人白介素-3，His-标签（无动物源） |
| 种属 | Human |
| 表达宿主 | HEK 293 Cells |
| 纯度 | >95% as determined by SDS-PAGE |
| 内毒素 | < 1 EU per µgof the protein as determined by the LALmethod. |
| 生物活性 | Measured by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is 6.87 ng/mL,The specific activity of recombinant Human IL-3 protein is approximately 1.46 x 105 IU/mg. |
| 基因编号 | 3562 |
| 蛋白链接 | https://www.uniprot.org/uniprotkb/P08700/entry |
| 别名 | IL-3; Hematopoietic growth factor; Mast cell growth factor (MCGF); Multipotential colony-stimulating factor; P-cell-stimulating factor |
| 蛋白序列 | MSRLPVLLLLQLLVRPGLQAPMTQTTPLKTSWVNCSNMIDEIITHLKQPPLPLLDFNNLNGEDQDILMENNLRRPNLEAFNRAVKSLQNASAIESILKNLLPCLPLATAAPTRHPIHIKDGDWNEFRRKLTFYLKTLENAQAQQTTLSLAIF |
| 蛋白标签 | C-His |
| 预测分子量 | The recombinant human IL-3 protein consists of 140 amino acids and predicts a molecular mass of 16kD.The apparent molecular mass of the human IL-3 is approximately 17-35 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
| 产品形式 | Lyophilized from sterile PBS, pH 7.4. |
| 使用方式 | Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human IL-3 protein in the buffer which we provide not less than 100 µg/mL, which can then be further diluted to other aqueous solutions. |
| 运输方式 | The product is shipped at ambient temperature. |
| 储存条件 | Store at -20℃ |
| 产品背景 | Human interleukin-3 (hIL-3) is a therapeutically important cytokine involved in the maturation and differentiation of various cells of the immune system. IL-3 predominantly produced by activated T lymphocytes, stimulates both endothelial cell proliferation and functional activation. Unlike other cytokines, IL-3 is a cytokine with a multilineage potential and broad spectrum of target cells and it plays a vital role in hematopoiesis. Due to its common receptor subunit, the action of IL-3 shows functional redundancy with other cytokines such as the granulocyte-macrophage colony-stimulating factor and IL-5. IL-3 has been successfully used in ameliorating radiation-induced bone marrow aplasia and similar conditions. |
*本产品仅供科研试验用，不可直接用于人体。
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